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Supplementary Fig. 2 from Pancreatic Cancer–Derived Exosomes Cause Paraneoplastic β-cell Dysfunction

Year: 2023

Type: supplementary-materials

Abstract: Supplementary Fig. 2. PC-derived exosomes from additional PC cell lines and PC patient plasma can decrease insulin secretion. (A-B) PC-Exo isolated from 2 PC patient-derived cell lines decreased insulin secretion in INS-1 cells. (C-D) PC-Exo isolated from 2 different PC patient blood plasma samples can decrease insulin secretion at varying levels. * P<.05; ** P<.001.

DOI: 10.1158/1078-0432.22459896

Authors: Naureen Javeed, Gunisha Sagar, Shamit K. Dutta, Thomas C. Smyrk, Julie S. Lau, Santanu Bhattacharya, Mark Truty, Gloria M. Petersen, Randal J. Kaufman, Suresh T. Chari, Debabrata Mukhopadhyay

Language: English

Topic: Extracellular vesicles in disease

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362397826

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