Supplemental Materials from Clinical Relevance of KRAS-Mutated Subclones Detected with Picodroplet Digital PCR in Advanced Colorectal Cancer Treated with Anti-EGFR Therapy
Year: 2023
Type: supplementary-materials
Abstract: Supplemental Materials. Supplemental Table 1: Patient mutational status and agreement between qPCR, dPCR and sequencing results. Supplemental Table 2: Analysis of different tissue samples coming from the same patient. Supplemental Figure 1: Fraction of mutated alleles (including multiple subclones) in the patients detected by both conventional and droplet-digital PCR procedures. Supplemental Figure 2: Fraction of mutated DNA observed for the different tested mutations of KRAS and BRAF.
Authors: Pierre Laurent-Puig, Deniz Pekin, Corinne Normand, Steve K. Kotsopoulos, Philippe Nizard, Karla Perez-Toralla, Rachel Rowell, Jeff Olson, Preethi Srinivasan, Delphine Le Corre, Thevy Hor, Zakaria El Harrak, Xinyu Li, Darren R. Link, Olivier Bouché, Jean-François Emile, Bruno Landi, Valérie Boige, J. Brian Hutchison, Valerie Taly
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4361919597