SI Tables from Myeloma Cell Dynamics in Response to Treatment Supports a Model of Hierarchical Differentiation and Clonal Evolution
Year: 2023
Type: other
Abstract: Supplementary Table S1. Summary statistics of the estimated slopes and turning points for the model fitting of the six cohorts from the three trials. Supplementary Table S2. Information on the number of data points in the pre-treatment phase, phase during administration of therapy, and posttreatment phase. Supplementary Table S3. Summary statistics of slopes and turning points for the treatment response data of the VISTA, MMY-2001, and APEX trials. Supplementary Table S4. Dependence of MM stage, prior administration of steroids, and the best-fitting model. Supplementary Table S5. Counts of death for single-phasic and 2-phasic patients as well as different sub-cohorts based on modeling parameters in the VISTA MP and VISTA VMP cohort during treatment. Supplementary Table S6. Summary statistics of the day differences between scheduled and actual visit dates for during-treatment response data for the VISTA MP and VISTA VMP cohort. Supplementary Table S7. Parameter values used for the hybrid mathematical model for all three cohorts.
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4362401177