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Supplementary Figures from SNP rs16906252C>T Is an Expression and Methylation Quantitative Trait Locus Associated with an Increased Risk of Developing MGMT-Methylated Colorectal Cancer

Year: 2023

Type: supplementary-materials

Abstract: Supplementary Figure 1. Allele quantification assays used to measure relative levels of mRNA expression at exonic SNPs within MGMT. Supplementary Figure 2. Allelic expression ratios of MGMT transcripts in the normal colorectal mucosa (NCM) of colorectal cancer (CRC) patients as measured by allele quantification (AQ) pyrosequencing at exon 3 SNP rs1803965.

DOI: 10.1158/1078-0432.22467926

Authors: Joice Kuroiwa-Trzmielina, Fan Wang, Robert W. Rapkins, Robyn L. Ward, Daniel D. Buchanan, Aung Ko Win, Mark Clendenning, Christophe Rosty, Melissa C. Southey, Ingrid M. Winship, John L. Hopper, Mark A. Jenkins, Jake Olivier, Nicholas J. Hawkins, Megan P. Hitchins

Language: English

Topic: Genetic factors in colorectal cancer

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361931058

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