Supplementary Data from The sTRA Plasma Biomarker: Blinded Validation of Improved Accuracy Over CA19-9 in Pancreatic Cancer Diagnosis
Year: 2023
Type: supplementary-materials
Abstract: Supplementary Methods: 1. Sandwich immunoassays on microarrays. 2. Processing the samples and the biomarker data. 3. Immunofluorescence on tissue microarrays. 4. Cell culture and measuring cell-surface sTRA and CA19-9. 5. Patient-derived xenografts. Supplementary Tables (provided as separate Excel files): Table S1. Training and validation set data. Table S2. Covariates. Table S3. Application of the specificity-optimized panel to the test set. Table S4. Application of the specificity-optimized panel to the test set. Supplementary Figures: Figure S1. Correlations between secreted levels and cellular expression. Figure S2. Individual marker performance in stage I-II and stage III-IV cancers.
Authors: Ben Staal, Ying Liu, Daniel Barnett, Peter Hsueh, Zonglin He, ChongFeng Gao, Katie Partyka, Mark W. Hurd, Aatur D. Singhi, Richard R. Drake, Ying Huang, Anirban Maitra, Randall E. Brand, Brian B. Haab
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4361935220