Work

Figure S1 from Genomic Profiling of Prostate Cancers from Men with African and European Ancestry

Year: 2023

Type: other

Abstract: Associations of recurrent deletion events of selected genes with Gleason score and race in TCGA and AAPC cohorts. Left: Amplification frequencies were associated with race and Gleason score while controlling for age using samples from TCGA and AAPC cohorts with genome-wide copy number ratio data (AFR: 157, EUR: 392). A purple dot indicates statistically significant association with race (FDR < 0.05). The solid black line represents a 1:1 relationship between AFR and EUR patients. Genes that did not have a significant association (FDR >= 0.05) with race are indicated by an open dot. Right: Deletion frequencies for PTEN, ZFHX3, and ETV3 are shown in AFR and EUR men.

DOI: 10.1158/1078-0432.22476986

Authors: Yusuke Koga, Hanbing Song, Zachary R. Chalmers, Justin Newberg, Eejung Kim, Jian Carrot-Zhang, Daphnee Piou, Paz Polak, Sarki A. Abdulkadir, Elad Ziv, Matthew Meyerson, Garrett M. Frampton, Joshua D. Campbell, Franklin W. Huang

Language: English

Topic: Prostate Cancer Treatment and Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362409952

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