Supplementary Figures 1-3 from PLZF Confers Effector Functions to Donor T Cells That Preserve Graft-versus-Tumor Effects while Attenuating GVHD
Year: 2023
Type: supplementary-materials
Abstract: Supplementary S1: PLZF expression affects CD4+ driven alloreactivity. Supplementary S2: PLZF-TG T cells undergo allo-activation that is similar to donor B6-WT T cells. Supplementary S3: Fewer deaths from GVHD are seen in BMT recipients of PLZF-TG T cells compared to the BMT recipients of B6-WT T cells.
Authors: Arnab Ghosh, Amanda M. Holland, Yildirim Dogan, Nury L. Yim, Uttam K. Rao, Lauren F. Young, Mallory L. West, Natalie V. Singer, Hae Lee, Il-Kang Na, Jennifer J. Tsai, Robert R. Jenq, Olaf Penack, Alan M. Hanash, Cecilia Lezcano, George F. Murphy, Chen Liu, Michel Sadelain, Martin G. Sauer, Derek Sant'Angelo, Marcel R.M. van den Brink
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4362419018