Supplementary Methods, Figures 1 - 10, Tables 1 - 3 from Targeting ROR1 Inhibits Epithelial–Mesenchymal Transition and Metastasis
Year: 2023
Type: supplementary-materials
Abstract: PDF file - 1112K, Supplementary Figure 1: Surface Expression Of ROR1 Associates With Breast Cancer Cell-lines That Have High-metastatic Potential. Supplementary Figure 2: High-level Expression of ROR1 In Breast Cancer Is Associated With Shorter Lung, Bone and Brain Metastasis-free Survival. Supplementary Figure 3: High-Level Expression Of ROR1 In Breast Cancer Is Associated With Shorter Metastasis-Free Survival, and Independent from their ER, PR and HER2 status. Supplementary Figure 4. Expression of ROR1 By Breast Cancer Cell Lines Is Associated With Features Of EMT. Supplementary Figure 5: Silencing ROR1 Reduces Expression Of CXCR4. Supplementary Figure 6. Silencing ROR1 Regulates EMT Genes expression. Supplementary Figure 7: Silencing ROR1 Effects Modest Late-Growth Inhibition Of Orthotopic Xenografts At The Site Of Injection But Strong Inhibition Of Experimental Pulmonary Metastases. Supplementary Figure 8: Immunohistochemistry of Experimental Metastatic Foci. Supplementary Figure 9. Silencing ROR1 Reduces Pulmonary Metastasis And Bone Metastasis Of MDA-MB-231 Derived Cell lines LM2-4175 And BoM-1833 In Vivo. Supplementary Figure 10: Silencing ROR1 Inhibits Migration Of HS-578T and BT549 Migration In Vitro. Supplementary Table 1: Summary Of Human Breast Cancer Cell Line Characteristics With Respect To EMT Status, Subgrouping, Invasiveness And Matrigel Morphology. Supplementary Table 2: Correlation Of ROR1 Status With Various Clinical Features Of Breast Cancer. Supplementary Table 3: Expression Of ROR1 Serves As An Independent Risk Factor For Short Metastasis-free Survival.
Language: English
Topic: Cancer Cells and Metastasis
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4362419234