Supplementary Table S1 and Figures S1-S8 from CDK4/6 and IGF1 Receptor Inhibitors Synergize to Suppress the Growth of p16INK4A-Deficient Pancreatic Cancers
Year: 2023
Type: supplementary-materials
Abstract: Supplementary Table S1 and Figures S1-S5, related to Figure 1: Supporting information on the initial analysis that lead to the study and on the synergy of IGF1R/IR and CDK4/6 inhibitors Supplementary Figure S6 and S7, related to Figure 3: Xenograft tumor staining for senescence marker H3K9me3 and pRB phosphorylation upon treatment with drug combination in vitro Supplementary Figure S8, related to Figure 6: Synergy plots for mTOR and CDK4/6 inhibitor combination
Authors: Andreas M. Heilmann, Rushika M. Perera, Veronika Ecker, Brandon N. Nicolay, Nabeel Bardeesy, Cyril H. Benes, Nicholas J. Dyson
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4362419833