Supplementary Figures S1-S5 from CDC42 Inhibition Suppresses Progression of Incipient Intestinal Tumors
Year: 2023
Type: supplementary-materials
Abstract: Epithelial deletion of Cdc42 abrogates APCMin/+ tumorigenesis (S1); Improved body weight in Catnb(ex3)/+;Cdc42fl/+;Vil-Cre mice (S2); Epithelial Cdc42 deletion alleviated formation of crypt-like foci (S3); Cdc42 deletion reduced Paneth-like cells in microadenoma foci (S4); CASIN treatment arrested LIM1863 tumor organoids (S5).
Authors: Ryotaro Sakamori, Shiyan Yu, Xiao Zhang, Andrew Hoffman, Jiaxin Sun, Soumyashree Das, Pavan Vedula, Guangxun Li, Jiang Fu, Francesca Walker, Chung S. Yang, Zheng Yi, Wei Hsu, Da-Hai Yu, Lanlan Shen, Alexis J. Rodriguez, Makoto M. Taketo, Edward M. Bonder, Michael P. Verzi, Nan Gao
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4362420263