Supplementary Table 1 and Supplementary Figures 1 through 7 from Tetraspanin CD81 Promotes Tumor Growth and Metastasis by Modulating the Functions of T Regulatory and Myeloid-Derived Suppressor Cells
Year: 2023
Type: supplementary-materials
Abstract: Supplementary Table 1: Antibodies used in this study. Supplementary Figure 1: CD81 expression on tumor cell lines. Supplementary Figure 2: Analysis of purified CD4+CD25+ Tregs for FoxP3 expression. Supplementary Figure 3: Tregs from LLC and E0771 tumor bearing CD81KO C57BL6 mice are less suppressive. Supplementary Figure 4: Naive BALB/c WT or CD81 KO T CD4+ cells are equally suppressed by WT, HT or CD81 KO Tregs. Supplementary Figure 5: Analysis of the indicated proteins (A) and mRNA (B) expression in purified WT or CD81KO MDSCs. Supplementary Figure 6: Analysis of ROS levels measured in MDSCs and Lymphocytes in WT, HT or CD81KO C57BL/6 mice. Supplementary Figure 7: WT and CD81KO Tregs express similar levels of the indicated markers.
Language: English
Topic: T-cell and B-cell Immunology
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4362420628