Work

Supplementary Figures from HOXB13 Mediates Tamoxifen Resistance and Invasiveness in Human Breast Cancer by Suppressing ERα and Inducing IL-6 Expression

Year: 2023

Type: supplementary-materials

Abstract: PDF file, 159K, Figure S1: Characterization of HOXB13 expression in breast cancer cell lines in vitro and in vivo ; Figure S2: HOXB13 and ERα expression in tamoxifen-resistant MCF-7 cell lines, and reversal of tam-resistance by depletion of HOXB13. ; Figure S3: HOXB13 promotes stromal recruitment through expression of IL6.

DOI: 10.1158/0008-5472.22397562.v1

Authors: Nilay Shah, Kideok Jin, Leigh-Ann Cruz, Sunju Park, Helen Sadik, Soonweng Cho, Chirayu Pankaj Goswami, Harikrishna Nakshatri, Rajnish Gupta, Howard Y. Chang, Zhe Zhang, Ashley Cimino-Mathews, Leslie Cope, Christopher Umbricht, Saraswati Sukumar

Language: English

Topic: Estrogen and related hormone effects

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362421315

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