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Supplemental Figure S1 from Therapeutically Active RIG-I Agonist Induces Immunogenic Tumor Cell Killing in Breast Cancers

Year: 2023

Type: supplementary-materials

Abstract: A. METABRIC-curated clinical dataset of invasive breast cancers (N = 817, Ref. here) was assessed for samples harboring genomic loss (solid blue boxes) or mRNA down-regulation (defined as < -2 S.D. from the mean DDX58 expression among the entire dataset, and shown in blue outline). B. A lollipop graph was used to show the relative positioning of DDX58 missense mutations found in a TCGA-curated clinical dataset of invasive breast tumors (N = 817). No recurrent mutations were identified.

DOI: 10.1158/0008-5472.22419410.v1

Authors: David L. Elion, Max E. Jacobson, Donna J. Hicks, Bushra Rahman, Violeta Sanchez, Paula I. Gonzales-Ericsson, Olga Fedorova, Anna M. Pyle, John T. Wilson, Rebecca S. Cook

Language: English

Topic: interferon and immune responses

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362422823

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