Figure S2 from Genomic and Epigenomic Landscaping Defines New Therapeutic Targets for Adenosquamous Carcinoma of the Pancreas
Year: 2023
Type: other
Abstract: A-B) DNA content histograms and genomic profiles of flow sorted diploid only ASCP biopsies. A) female (two copies of chromosome X) and; B) male (one copy of chromosome X) diploid only ASCP biopsies. In both cases the 4.0N fractions were <6% of the sample. C) DNA content histograms of ASCP PDX models. Each sample had a mouse host (green) and at least one tumor peak (red). All PDX samples were flow sorted prior to CNV, exome, and ATAC-seq analysis.
Authors: Elizabeth Lenkiewicz, Smriti Malasi, Tara L. Hogenson, Luis F. Flores, Whitney Barham, William J. Phillips, Alexander S. Roesler, Kendall R. Chambers, Nirakar Rajbhandari, Akimasa Hayashi, Corina E. Antal, Michael Downes, Paul M. Grandgenett, Michael A. Hollingsworth, Derek Cridebring, Yuning Xiong, Jeong-Heon Lee, Zhenqing Ye, Huihuang Yan, Matthew C. Hernandez, Jennifer L. Leiting, Ronald M. Evans, Tamas Ordog, Mark J. Truty, Mitesh J. Borad, Tannishtha Reya, Daniel D. Von Hoff, Martin E. Fernandez-Zapico, Michael T. Barrett
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4362423729