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Supplementary Figure 7 from Resistance to BRAF Inhibition in BRAF-Mutant Colon Cancer Can Be Overcome with PI3K Inhibition or Demethylating Agents

Year: 2023

Type: supplementary-materials

Abstract: PDF file - 46K, HT29 and Colo205 parental and PLX-resistant (RC) cell lines were profiled by Affymetrix U133A for gene expression. Additional candidate genes in the MAPK and AKT pathway are shown below. Each point represents the relative expression of a single probe (relative expression of resistant cell to parental) for each of the specified genes.

DOI: 10.1158/1078-0432.22445826

Authors: Muling Mao, Feng Tian, John M. Mariadason, Chun C. Tsao, Robert Lemos, Farshid Dayyani, Y.N. Vashisht Gopal, Zhi-Qin Jiang, Ignacio I. Wistuba, Xi M. Tang, William G. Bornman, Gideon Bollag, Gordon B. Mills, Garth Powis, Jayesh Desai, Gary E. Gallick, Michael A. Davies, Scott Kopetz

Language: English

Topic: Colorectal Cancer Treatments and Studies

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361881680

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