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Supplementary Figures 1 - 6 from Safety and Preliminary Evidence of Biologic Efficacy of a Mammaglobin-A DNA Vaccine in Patients with Stable Metastatic Breast Cancer

Year: 2023

Type: supplementary-materials

Abstract: Supplementary Figure 1: Expression of MAM-A and HLA-A2 in breast cancer cell lines. Supplementary Figure 2: MAM-A DNA vaccination increases breast cancer-induced TNF-α production by MAM-A-specific CD8 T cells. Supplementary Figure 3: MAM-A DNA vaccination increases NKG2D expression in MAM-A-specific CD8 T cells. Supplementary Figure 4: MAM-A DNA vaccination increases DAP10 adapter protein expression in MAM-A-specific CD8 T cells. Supplementary Figure 5: MAM-A DNA vaccination increases perforin expression in MAM-A-specific CD8 T cells. Supplementary Figure 6: Therapy received by the patients (screen failed and vaccinated).

DOI: 10.1158/1078-0432.22455551

Authors: Venkataswarup Tiriveedhi, Natalia Tucker, John Herndon, Lijin Li, Mark Sturmoski, Matthew Ellis, Cynthia Ma, Michael Naughton, A. Craig Lockhart, Feng Gao, Timothy Fleming, Peter Goedegebuure, Thalachallour Mohanakumar, William E. Gillanders

Language: English

Topic: Immunotherapy and Immune Responses

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362433397

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