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Supplementary Data from Inhibition of Pyruvate Dehydrogenase Kinase Enhances the Antitumor Efficacy of Oncolytic Reovirus

Year: 2023

Type: supplementary-materials

Abstract: Supplemental figures 1-6 contain metabolomic, proteomic, extracellular flux analysis, cell death, and in vivo data supporting our findings that pyruvate dehydrogenase activity influences oncolytic viral therapy.

DOI: 10.1158/0008-5472.22421376

Authors: Barry E. Kennedy, John Patrick Murphy, Derek R. Clements, Prathyusha Konda, Namit Holay, Youra Kim, Gopal P. Pathak, Michael A. Giacomantonio, Yassine El Hiani, Shashi Gujar

Language: English

Topic: Virus-based gene therapy research

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362446511

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