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Supplementary Figures 1 - 5 from Epigenetic Repression of miR-31 Disrupts Androgen Receptor Homeostasis and Contributes to Prostate Cancer Progression

Year: 2023
Type: supplementary-materials
Abstract: PDF file - 1891K, Supplementary Fig. S1. Identification of 105 differential expressed miRNAs in PCA, deletion analysis for Chr. 9p21.3, and DNA methylation analysis of the miR-31 promoter region Supplementary Fig. S2. AR-signaling negatively regulates the expression of miR-31. Supplementary Fig. S3. miR-31 negatively regulates AR and E2F1. Supplementary Fig. S4. miR-31 directly targets key cell cycle players. Supplementary Fig. S5. miR-31 inhibits growth the VCaP xenografts.
DOI: 10.1158/0008-5472.22398807
Authors: Pei-Chun Lin, Ya-Lin Chiu, Samprit Banerjee, Kyung Park, Juan Miguel Mosquera, Eugenia Giannopoulou, Pedro Alves, Ashutosh K. Tewari, Mark B. Gerstein, Himisha Beltran, Ari M. Melnick, Olivier Elemento, Francesca Demichelis, Mark A. Rubin
Language: English
Subfield: Cancer Research
Open Access status: gold
OpenAlex ID: W4362461157
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