Supplementary Methods, Tables 1 - 6, Figures 1 - 5 from APOBEC3B Upregulation and Genomic Mutation Patterns in Serous Ovarian Carcinoma
Year: 2023
Type: supplementary-materials
Abstract: PDF file - 481K, Table S1: Cell line information Table S2: Quantitative PCR primer and probe sequences. Table S3: Non-malignant tissues tested Table S4: Early stage serous ovarian tumors used in sequence analyses Table S5: Additional ovarian tumor specimens analyzed Table S6: Microarray analysis of APOBEC3 and select control gene probe sets in ovarian TCGA data Figure S1: Polynucleotide cytosine deaminase expression in ovarian cell lines. Figure S2: Endogenous DNA deaminase activity in APOBEC3B high and low cell lines. Figure S3: Endogenous APOBEC3B activity on alternate dinucleotide substrates. Figure S4: Polynucleotide cytosine deaminase expression in ovarian primary samples. Figure S5: Polynucleotide cytosine deaminase expression in ovarian TCGA samples by RNAseq.
Authors: Brandon Leonard, Steven N. Hart, Michael B. Burns, Michael A. Carpenter, Nuri A. Temiz, Anurag Rathore, Rachel I. Vogel, Jason B. Nikas, Emily K. Law, William L. Brown, Ying Li, Yuji Zhang, Matthew J. Maurer, Ann L. Oberg, Julie M. Cunningham, Viji Shridhar, Debra A. Bell, Craig April, David Bentley, Marina Bibikova, R. Keira Cheetham, Jian-Bing Fan, Russell Grocock, Sean Humphray, Zoya Kingsbury, John Peden, Jeremy Chien, Elizabeth M. Swisher, Lynn C. Hartmann, Kimberly R. Kalli, Ellen L. Goode, Hugues Sicotte, Scott H. Kaufmann, Reuben S. Harris
Language: English
Subfield: Reproductive Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4362461419