Work

Data from Moving Spatially Resolved Multiplexed Protein Profiling toward Clinical Oncology

Year: 2023

Type: other

Abstract: Summary: The shift in cancer therapy from broadly cytotoxic agents toward “personalized” treatments that target specific alterations in each patient's tumor requires diagnostic pathology approaches that are quantitative and biospecimen-friendly. Novel multiplexed antibody-based imaging technologies can measure single-cell expression of over 60 proteins in intact tumor sections and hold promise for clinical oncology.

Authors: Maryam Pourmaleki, Nicholas D. Socci, Travis J. Hollmann, Ingo K. Mellinghoff

Institutions: Memorial Sloan Kettering Cancer Center, Bristol-Myers Squibb (United States), Weill Cornell Medicine

Language: English

Topic: Advanced Biosensing Techniques and Applications

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362479647

Cites: 12

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Related to: 10