Work

Supplementary Figures S1 - S4 from Genome-Wide Gene Expression Changes in the Normal-Appearing Airway during the Evolution of Smoking-Associated Lung Adenocarcinoma

Year: 2023

Type: supplementary-materials

Abstract: S1. Lung tumor development in NNK-exposed Gprc5a-/- mice. S2. Evolutionarily conserved patterns of tobacco-carcinogen mediated gene expression in murine and human airway epithelia. S3. Early and persistent changes in mouse airway gene expression in vivo following tobacco carcinogen exposure and during lung oncogenesis. S4. Gene profiles downregulated in the mouse normal-appearing airway field of injury are overall suppressed in lung tumors relative to adjacent normal lung.

DOI: 10.1158/1940-6207.22533308

Authors: Jacob Kantrowitz, Ansam Sinjab, Li Xu, Tina L. McDowell, Smruthy Sivakumar, Wenhua Lang, Sayuri Nunomura-Nakamura, Junya Fukuoka, Georges Nemer, Nadine Darwiche, Hassan Chami, Arafat Tfayli, Ignacio I. Wistuba, Paul Scheet, Junya Fujimoto, Avrum E. Spira, Humam Kadara

Language: English

Topic: Lung Cancer Research Studies

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362480792

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