Supplementary Tables S1-S7; Supplementary Figures S1-S2; and Supplementary Materials & Methods from Optimization of RGD-Containing Cyclic Peptides against αvβ3 Integrin
Year: 2023
Type: supplementary-materials
Abstract: General methods for library synthesis Table S1. MS and purity for cyclic peptide 1 derivatives Synthesis of focused libraries Table S2. Amino acids used in the synthesis of focused Library 1 and 2 Table S3. Amino acids used in the synthesis of focused Library 1. Table S4. Amino acids used in the synthesis of focused Library 2 NMR study of peptide 1 and 4 Experimental Constraints and Structure Calculation Table S5. Chemical shifts of peptide 1 at 295K, DMSO-d6. Table S6. Chemical shifts of peptide 4 at 295K, DMSO-d6. Table S7. Structure statistics for the ensembles of 15 calculated structures of peptide 1 and peptide 4 Figure S1. Representative regions of the 2D NOESY spectrum of 1 and 4. Figure S2. Superimposed solution structures are the ensembles of 15 structures for peptide 1 and 4. In vivo and ex vivo optical imaging Abbreviations Reference
Language: English
Subfield: Immunology and Allergy
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4362482086