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Supplement Figure 1 from Targeting Mitochondrial Proline Dehydrogenase with a Suicide Inhibitor to Exploit Synthetic Lethal Interactions with p53 Upregulation and Glutaminase Inhibition

Year: 2023
Type: other
Abstract: Supplement Figure 1. Mitochondria isolated from ZR-75-1 cells and assayed for PRODH activity assessed by either P5C production (A) or substrate inducing NADH formation (B), with use of NADH bioassay to compare PRODH inhibitor effects (C, D).
DOI: 10.1158/1535-7163.22506039
Authors: Gary K. Scott, Christina Yau, Beatrice C. Becker, Sana Khateeb, Sophia Mahoney, Martin Borch Jensen, Byron Hann, Bryan J. Cowen, Scott D. Pegan, Christopher C. Benz
Language: English
Subfield: Biochemistry
Open Access status: gold
OpenAlex ID: W4362482269
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