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Supplementary Figure S7 from Rapid Induction of Apoptosis by PI3K Inhibitors Is Dependent upon Their Transient Inhibition of RAS–ERK Signaling

Year: 2023

Type: supplementary-materials

Abstract: PDF file 1129K, Supplementary Figure S7. Combined MEK and AKT inhibition improves antitumor efficacy in vivo. Pulsatile administration of the PI3K inhibitor is effective. Related to main Figure 7

DOI: 10.1158/2159-8290.22530251.v1

Authors: Marie Will, Alice Can Ran Qin, Weiyi Toy, Zhan Yao, Vanessa Rodrik-Outmezguine, Claudia Schneider, Xiaodong Huang, Prashant Monian, Xuejun Jiang, Elisa de Stanchina, José Baselga, Ningshu Liu, Sarat Chandarlapaty, Neal Rosen

Language: English

Topic: PI3K/AKT/mTOR signaling in cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362482370

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