Supplemental Figure 1-5 from Co-targeting HGF/cMET Signaling with MEK Inhibitors in Metastatic Uveal Melanoma
Year: 2023
Type: supplementary-materials
Abstract: Supplemental Figure 1: HGF inhibits trametinib-induced apoptosis in UM cells; Supplemental Figure 2: Bim-EL or Bmf expression renders UM cells susceptible to apoptosis; Supplemental Figure 3: Human hepatic stellate cell (HHSteC) conditioned medium activates HGF-cMET signaling; Supplemental Figure 4: Human hepatic stellate cell (HHSteC) conditioned medium effects on migration and invasion of UM cells; Supplemental Figure 5: Isoform specific PI3K inhibitors differentially block HGF-mediated activation of AKT in UM001 cells.
Language: English
Subfield: Ophthalmology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4362482700