Supplementary Figures 1-10 from Loss of 53BP1 Causes PARP Inhibitor Resistance in Brca1-Mutated Mouse Mammary Tumors
Year: 2023
Type: supplementary-materials
Abstract: PDF file - 1.2MB, This file contains additional data on tumor responses to olaparib treatment (Fig. S1 and S2), pH2AX stainings on treated and untreated tumors (Fig. S3), analysis of mutations in 53BP1 (Fig. S4 and S7B), characterization of cell lines (Fig. S5), RAD51 and 53BP1 IRIFs in tumors and cell lines (Fig. S6 and S7), 53BP1 in topotecan-resistant tumors (Fig. S8) and tumor responses to AZD2461 treatment (Fig. S9 and S10).
Authors: Janneke E. Jaspers, Ariena Kersbergen, Ute Boon, Wendy Sol, Liesbeth van Deemter, Serge A. Zander, Rinske Drost, Ellen Wientjens, Jiuping Ji, Amal Aly, James H. Doroshow, Aaron Cranston, Niall M.B. Martin, Alan Lau, Mark J. O'Connor, Shridar Ganesan, Piet Borst, Jos Jonkers, Sven Rottenberg
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4362483611