Work

Data from NF-κB Fans the Flames of Lung Carcinogenesis

Year: 2023

Type: other

Abstract: This perspective on Deng et al. (beginning on p. 424 in this issue of the journal) examines the link between NF-κB and lung tumorigenesis. Experiments in genetically engineered mouse models of lung cancers are elucidating protumorigenic roles of NF-κB activation in lung cancer pathogenesis. Our growing understanding of the tumor-promoting NF-κB downstream effector pathways could lead to the development of novel approaches for lung cancer therapy and chemoprevention. Cancer Prev Res; 3(4); 403–5. ©2010 AACR.

DOI: 10.1158/1940-6207.c.6544686.v1

Authors: Kwok-Kin Wong, Tyler Jacks, Glenn Dranoff

Institutions: Harvard University, Dana-Farber Cancer Institute, Howard Hughes Medical Institute, Koch Institute for Integrative Cancer Research At MIT, Massachusetts Institute of Technology

Language: English

Topic: NF-κB Signaling Pathways

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362485028

Cites: 22

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Related to: 10