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Supplementary Figures S1 and S2 from Key Survival Factor, Mcl-1, Correlates with Sensitivity to Combined Bcl-2/Bcl-xL Blockade

Year: 2023

Type: supplementary-materials

Abstract: S1. CCLE-curated cancer cells were grouped according to tumor type and assessed for miRNA expression for BCL2 and BCL2L1 (Bcl-xL) using cBio portal (www.cbio.org). S2. Whole cell lysates form a panel of breast cancer cell lines were assessed by western analysis (BL = Basal-like).

DOI: 10.1158/1541-7786.22511350.v1

Authors: Michelle M. Williams, Linus Lee, Donna J. Hicks, Meghan M. Joly, David Elion, Bushra Rahman, Courtney McKernan, Violeta Sanchez, Justin M. Balko, Thomas Stricker, Monica Valeria Estrada, Rebecca S. Cook

Language: English

Topic: Cell death mechanisms and regulation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362485802

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