All Supplementary Figures and Tables from The Germline Variants rs61757955 and rs34988193 Are Predictive of Survival in Lower Grade Glioma Patients
Year: 2023
Type: supplementary-materials
Abstract: S1. A boxplot representing the percentage of variants called in the whole exome sequenced (WXS) tumor sample that is likely somatic mutations. S2. Correlation between the variant allele frequencies calculated from the four variant sets and the distribution of allele frequencies. S3. Principal components calculated from germline variants from the whole exome sequencing data from the non-tumor samples. S4. Kaplan-Meier plot for the germline variant rs28672782 in BRSK2. Table S1. Quality control checks reveal that somatic mutations and RNA editing did not affect the results of our analysis. Table S2. Correlation between the allele frequencies calculated in our four variant sets and the allele frequencies reported by gnomAD. Table S3. Variants genetically linked to rs61757955 in the European population, the population that is most similar to the TCGA lower grade glioma patient population. Table S4. Results from testing for an association between the germline variant rs34988193 and genomic and histological variables.
Authors: Ajay Chatrath, Manjari Kiran, Pankaj Kumar, Aakrosh Ratan, Anindya Dutta
Language: English
Subfield: Genetics (clinical)
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4362486677