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Supplementary Tables 1-2, Figures 1-2 from Biological Responses to TGF-β in the Mammary Epithelium Show a Complex Dependency on Smad3 Gene Dosage with Important Implications for Tumor Progression

Year: 2023

Type: supplementary-materials

Abstract: PDF file - 249K, Biological responses to TGF-beta in the mammary epithelium show a complex dependency on Smad3 gene dosage with important implications for tumor progression Table S1. Primer pair sequences for RTQ-PCR. Table S2. Patient information for matched breast cancer and adjacent normal tissue mRNA used for Smad3 mRNA assessment. FIGURE S1. Effect of Smad3 genotype on TGF-beta -regulated activity of MMPs in IMECs. FIGURE S2. Effect of Smad3 genotype on regulation by TGF-beta of genes involved in EMT and invasion responses

DOI: 10.1158/1541-7786.22517566.v1

Authors: Ethan A. Kohn, Yu-an Yang, Zhijun Du, Yoshiko Nagano, Catherine M.H. Van Schyndle, Michelle A. Herrmann, Madeleine Heldman, Jin-Qiu Chen, Christina H. Stuelten, Kathleen C. Flanders, Lalage M. Wakefield

Language: English

Topic: TGF-β signaling in diseases

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362487320

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