Work

Figure S5 from Hormone-Dependent Prostate Cancers are Dependent on Rac Signaling for Growth and Survival

Year: 2023

Type: other

Abstract: Supplementary Figure 5. (A) PSA RT-PCR on LNCaP cells treated stimulated with DHT in the presence of Biclutamide (Bic), Enzalutamide (Enz) or GYS32661 (661). (B) Androgen Response Element (ARE) luciferase assay on LNCaP cells stimulated with 10 nM DHT in the presence of Biclutamide (Bic), Enzalutamide (Enz) or GYS32661 (32661). (C) Androgen Response Element (ARE) luciferase assay on VCap cells transfected with siNSC or siRac1 and stimulated with 10 nM DHT. (D) Western blot analysis of LNCaP cells stimulated with 10 nM DHT in the presence of Enzalutamide or GYS32661. (E) Western blot analysis of siNSC and siRac1 LNCaP cells stimulated with 10 nM DHT.

DOI: 10.1158/1535-7163.22522666

Authors: Erik T. Goka, Dayrelis T. Mesa Lopez, Marc E. Lippman

Language: English

Topic: Prostate Cancer Treatment and Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362488271

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