Supplementary Figure 3 from Activity of Combined Androgen Receptor Antagonism and Cell Cycle Inhibition in Androgen Receptor Positive Triple Negative Breast Cancer
Year: 2023
Type: supplementary-materials
Abstract: Single-cell RNAseq of AR expressing MDA-MB-453 TNBC cells. scRNAseq was performed on untreated MDA-MB-453 cells cultured in full serum media. Cells were divided in groups based on their expression of AR, ARLow and ARHigh. (A) tSNE plot of AR levels in cells clustered by gene expression. (B) IPA was performed on the genes differentially expressed between ARLow and ARHigh groups. Shown are the top 50 most significantly altered disease and function pathways and canonical pathways.
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4362488452