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Supplementary Data from Depatuxizumab Mafodotin (ABT-414)-induced Glioblastoma Cell Death Requires EGFR Overexpression, but not EGFRY1068 Phosphorylation

Year: 2023

Type: supplementary-materials

Abstract: Supplementary Figure 1 Sensitivity of glioma cell lines to ABT-414.A. The cells were exposed to 10 nM ABT-414 for 72 h.B. LN-229 EGFRvIII cells were pre-treated with AB806 for 1 h prior to ABT-414 treatment.Metabolic activity was assessed by MTT assay in A and B.

DOI: 10.1158/1535-7163.22521682

Authors: Caroline von Achenbach, Manuela Silginer, Vincent Blot, William A. Weiss, Michael Weller

Language: English

Topic: Glioma Diagnosis and Treatment

Subfield: Genetics (clinical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362489104

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