Work

Supplementary Figures 1 - 5 from ONC201 Targets AR and AR-V7 Signaling, Reduces PSA, and Synergizes with Everolimus in Prostate Cancer

Year: 2023

Type: supplementary-materials

Abstract: Supplementary Figure 1. UPR genes in DU145 cells. Supplementary Figure 2. ONC201 does not inhibit translocation of AR-GFP to the nucleus upon DHT treatment and does not induce AR degradation. Supplementary Figure 3. ONC201 partly synergizes with docetaxol. Supplementary Figure 4. ONC201 partly synergizes with crizotinib. Supplementary Figure 5. Biweekly measurements of mouse weights after the indicated treatments in different prostate cancer xenograft models.

DOI: 10.1158/1541-7786.22512811.v1

Authors: Avital Lev, Amriti R. Lulla, Brian C. Ross, Marie D. Ralff, Petr B. Makhov, David T. Dicker, Wafik S. El-Deiry

Language: English

Topic: Prostate Cancer Treatment and Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362493674

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