Work

Supplementary Data from Verticillin A Causes Apoptosis and Reduces Tumor Burden in High-Grade Serous Ovarian Cancer by Inducing DNA Damage

Year: 2023

Type: supplementary-materials

Abstract: Supplementary Figure S1 shows histone post-translational modifications (B) and qRT-PCR validation (C) of RNA-seq data for vehicle (DMSO) and verticillin A treated OVCAR8 cells. Supplementary Figure S2 shows Verticillin A-eNP synthesis procedure (A), scanning electron micrograph of verticillin A expansile nanoparticles (B) and calibration curve for verticillin A (C). Supplementary Figure S3 shows structure of verticillin A (A), 1H-NMR (B) and UPLC (C) data for estimating purity of verticillin A, Supplementary Figure S4 shows mitochondrial toxicity assay for verticillin A

DOI: 10.1158/1535-7163.22506304

Authors: Amrita Salvi, Chiraz Soumia M. Amrine, Julia R. Austin, KiAundra Kilpatrick, Angela Russo, Daniel Lantvit, Esther Calderon-Gierszal, Zachary Mattes, Cedric J. Pearce, Mark W. Grinstaff, Aaron H. Colby, Nicholas H. Oberlies, Joanna E. Burdette

Language: English

Topic: Ovarian cancer diagnosis and treatment

Subfield: Reproductive Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362494367

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