Work

Supplementary Figure 1 from Biomarker Signatures Correlate with Clinical Outcome in Refractory Metastatic Colorectal Cancer Patients Receiving Bevacizumab and Everolimus

Year: 2023

Type: supplementary-materials

Abstract: Hierarchical clustering analyses may identify potential patterns of marker expression and biologically relevant groupings. As an example, PDGF-AA and PDGF-BB are tightly clustered at baseline, indicating that if a patient had high PDGF-AA levels, PDGF-BB levels also tended to be high. This relationship is maintained at later time points (C2D1 and C3D1), as the clustering of PDGFs reflects similar patterns of change on-treatment.

DOI: 10.1158/1535-7163.22500117

Authors: Yingmiao Liu, Mark D. Starr, John C. Brady, Christel Rushing, Anuradha Bulusu, Herbert Pang, Wanda Honeycutt, Anthony Amara, Ivy Altomare, Hope E. Uronis, Herbert I. Hurwitz, Andrew B. Nixon

Language: English

Topic: Colorectal Cancer Treatments and Studies

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362526146

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