Work

Supplementary Figure 4 from 3D Growth of Cancer Cells Elicits Sensitivity to Kinase Inhibitors but Not Lipid Metabolism Modifiers

Year: 2023

Type: supplementary-materials

Abstract: Clustered heat map analysis of lipids in MDA-MB-468 and PC3 spheroids treated for 4 days with A. AKT, B. PI3K and C. mTOR inhibitor at different concentrations. All Lipids were compared against DMSO control. Side covariates indicate lipid families, and lipids within each family are sorted by name.

DOI: 10.1158/1535-7163.22508368

Authors: Dylan T. Jones, Alessandro Valli, Syed Haider, Qifeng Zhang, Elizabeth A. Smethurst, Zachary T. Schug, Barrie Peck, Eric O. Aboagye, Susan E. Critchlow, Almut Schulze, Eyal Gottlieb, Michael J.O. Wakelam, Adrian L. Harris

Language: English

Topic: PI3K/AKT/mTOR signaling in cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362527707

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