Supplementary Figures from Integrin α3β1 Can Function to Promote Spontaneous Metastasis and Lung Colonization of Invasive Breast Carcinoma
Year: 2023
Type: supplementary-materials
Abstract: PDF file, 707K, S1. Comparison of alpha3beta1 and alpha6beta4 integrin expression in 4T1 cell lines. S2. BLI of spontaneous and experimental metastasis (color) S3. Certain large primary mammary fat pad tumors exhibited substantial centralized zones of necrosis. S4. Silencing alpha3 integrin leads to fewer pulmonary metastases following mammary fat pad injection. S5. RNAi-mediated silencing of RhoC has no impact on 4T1 cell metastatic colonization. S6. Cox-2, matrix metalloproteinase, VEGF, and transendothelial migration assays. S7. MDA-MB-231 breast cancer cells do not secrete laminin-332 or laminin-511 or depend on alpha3 integrin in short term proliferation assays.
Language: English
Subfield: Immunology and Allergy
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4362528279