Supplementary Figures S1 - S16 from Synthetic Lethal Approaches Exploiting DNA Damage in Aggressive Myeloma
Year: 2023
Type: supplementary-materials
Abstract: Supplementary Figure S1. 53BP1 and RPA32 staining in MM cells. Supplementary Figure S2. Replicative stress markers in MM cells. Supplementary Figure S3. Replicative stress markers in peripheral blood mononuclear cells (PBMCs). Supplementary Figure S4. Phospho-histone H3 and phospho-H2A.X staining in MM cells. Supplementary Figure S5. 53BP1 and RPA32 in primary MM cells. Supplementary Figure S6. ATR in MM patient and cell lines. Supplementary Figure S7. Gene expression levels of probe sets related to oxidative stress in MM patients. Supplementary Figure S8. Oxidative stress markers in MM cells upon MYC modulation and N-Acetyl Cysteine, VE-821, or Ku55933 treatment. Supplementary Figure S9. Piperlongumine effects on MM cells. Supplementary Figure S10. Effects of arsenic trioxide treatment of MM cells. Supplementary Figure S11. Piperlongumine and glutathione in MM cells. Supplementary Figure S12. Piperlongumine on peripheral blood mononuclear cells (PBMCs). Supplementary Figure S13. Cytotoxicity effects of piperlongumine in combination with VE-821. Supplementary Figure S14. Cytotoxicity effects of arsenic trioxide in combination with VE-821. Supplementary Figure S15. Cytotoxicity effects of piperlongumine in combination with proteasome inhibitors. Supplementary Figure S16. Cytotoxicity effects of VE-821 in combination with proteasome inhibitors.
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4362531542