Work

Supplementary Methods, Figures S1 - S4 from Immunogenomics of Hypermutated Glioblastoma: A Patient with Germline POLE Deficiency Treated with Checkpoint Blockade Immunotherapy

Year: 2023

Type: supplementary-materials

Abstract: Supplementary Figure S1. Mutation Spectra of each subclonal population. Supplementary Figure S2. Somatic Copy Number calls. Top: Primary, Middle: C7-T2 Metastasis, Bottom: T7-8 Metastasis. Supplementary Figure S3. Mutation signatures derived for each subclone independently. Supplementary Figure S4: Expression of immune-related genes.

DOI: 10.1158/2159-8290.22531176

Authors: Tanner M. Johanns, Christopher A. Miller, Ian G. Dorward, Christina Tsien, Edward Chang, Arie Perry, Ravindra Uppaluri, Cole Ferguson, Robert E. Schmidt, Sonika Dahiya, George Ansstas, Elaine R. Mardis, Gavin P. Dunn

Institutions: Washington University in St. Louis, University of California, San Francisco, Barnes-Jewish Hospital, Alvin J. Siteman Cancer Center

Language: English

Topic: Cancer Immunotherapy and Biomarkers

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362531707

Cites: 15

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Related to: 10