Table S2 from Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases
Year: 2023
Type: other
Abstract: Table S2: Differentially Expressed Genes in Patient-Matched Melanoma Brain and Extracranial Metastases. Comprehensive list of the 494 differentially expressed genes (adjusted p<0.05) between 35 MBMs and 42 patient-matched ECMs (from 29 patients). Results acquired via EdgeR-limma-voom R packages. Gene names are listed according to HGNC nomenclature. "Log2FC" is the estimate of the log2-fold-change of the gene in MBMs relative to patient-matched ECMs. "AveExr" is the average log2-expression for the gene across all samples. "t" is the moderated t-statistic. "P.Value" is the nominal p-value. "Adj.P.Val" is the p-value corrected for multiple testing via Benjamini-Hochberg procedure. "B" is the log-odds that the gene is differentially expressed.
Authors: Grant M. Fischer, Ali Jalali, David A. Kircher, Won-Chul Lee, Jennifer L. McQuade, Lauren E. Haydu, Aron Y. Joon, Alexandre Reuben, Mariana P. de Macedo, Fernando C. L. Carapeto, Chendong Yang, Anuj Srivastava, Chandrashekar R. Ambati, Arun Sreekumar, Courtney W. Hudgens, Barbara Knighton, Wanleng Deng, Sherise D. Ferguson, Hussein A. Tawbi, Isabella C. Glitza, Jeffrey E. Gershenwald, Y. N. Vashisht Gopal, Patrick Hwu, Jason T. Huse, Jennifer A. Wargo, P. Andrew Futreal, Nagireddy Putluri, Alexander J. Lazar, Ralph J. DeBerardinis, Joseph R. Marszalek, Jianjun Zhang, Sheri L. Holmen, Michael T. Tetzlaff, Michael A. Davies
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4362532032