Supplementary Figure S7 from Targeting CD20+ Aggressive B-cell Non–Hodgkin Lymphoma by Anti-CD20 CAR mRNA-Modified Expanded Natural Killer Cells In Vitro and in NSG Mice
Year: 2023
Type: supplementary-materials
Abstract: Supplementary Fig.S7: Proposed scientific model We propose that the interaction between anti-CD20 CAR on exPBNK and CD20 on the surface of B-L/L transmits activating signal back to exPBNK and significantly stimulates exPBNK degranulation and release of cytokine such as IFN-y to lyse resistant tumor targets.
Language: English
Topic: CAR-T cell therapy research
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4362532511