Supplementary Tables S1-S2 and Supplementary Figures S1-S11 from The DNA Endonuclease Mus81 Regulates ZEB1 Expression and Serves as a Target of BET4 Inhibitors in Gastric Cancer
Year: 2023
Type: supplementary-materials
Abstract: Supplementary Table S1: The primers for qRT-PCR; Supplementary Table S2: The primers for CHIP; Supplementary Figure S1: Mus81 expression changes in different gastric cancer tissues; Supplementary Figure S2: Cell migration correlates with Mus81 levels in gastric cancer cells; Supplementary Figure S3: Efficiency of Mus81 silencing and overexpression; Supplementary Figure S4: Mus81 had limited effect on cell proliferation of gastric cancer in vitro and in vivo; Supplementary Figure S5: Mus81 has no effect on cell cycle in gastric cancer cells; Supplementary Figure S6: Knockdown Mus81 has no effect on the expression of ZEB2, Twist1 and Snail; Supplementary Figure S7: The chemical structures of small molecular inhibitors chemical structures; Supplementary Figure S8: BRD4 does not directly regulate the expression of Mus81; Supplementary Figure S9: Heatmap of the genes co-expressed with Mus81 in 517 gastric cancer tissues and 36 gastric cancer cell lines; Supplementary Figure S10: AZD5153 decreases gastric cancer cells metastasis via Mus81 in vivo; Supplementary Figure S11: Schematic model of BRD4-Sirt5-Mus81-ZEB1 axis was shown.
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4362534944