Work

Supplement Information - Revised from Combination Treatment with Orlistat-Containing Nanoparticles and Taxanes Is Synergistic and Enhances Microtubule Stability in Taxane-Resistant Prostate Cancer Cells

Year: 2023

Type: other

Abstract: Supplementary Figure S1. Dose-response curves of combinations of orlistat or NanoOrl with taxanes; Supplementary Figure S2. Synergy analysis with Combenefit (Loewe model);Supplementary Figure S3. Synergy analysis with Combenefit [Highest Single Agent (HSA) model];Supplementary Figure. S4. Morphological changes associated with combination treatment;Supplementary Figure S5. Combination of NanoOrl plus docetaxel stabilizes microtubules in taxane-resistant cells;Supplementary Fig. S6. Example of overestimation of synergy; Supplementary Fig. S7. Example of underestimation of synergy.

DOI: 10.1158/1535-7163.22508233.v1

Authors: Joshua J. Souchek, Amanda L. Davis, Tanner K. Hill, Megan B. Holmes, Bowen Qi, Pankaj K. Singh, Steven J. Kridel, Aaron M. Mohs

Institutions: Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Wake Forest University Health Sciences

Language: English

Topic: Prostate Cancer Treatment and Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362535162

Cites:

Cited by:

Related to: 10