Work

Supplementary Figures 1-5 from Inhibition of Discoidin Domain Receptor 1 Reduces Collagen-mediated Tumorigenicity in Pancreatic Ductal Adenocarcinoma

Year: 2023

Type: supplementary-materials

Abstract: Supplementary Figure 1: 7rh reduces collagen-mediated signaling in a concentration-dependent manner in vivo; Supplementary Figure 2: 7rh inhibits Ddr1 activation in Pan02 tumors; Supplementary Figure 3: Inhibition of Ddr1 with 7rh does not induce observable toxicity; Supplementary Figure 4: 7rh in combination with chemotherapy reduced collagen deposition and AsPC-1 tumor weight; Supplementary Figure 5: 7rh in combination with chemotherapy reduced collagen deposition and KPC tumor weight

DOI: 10.1158/1535-7163.22508715.v1

Authors: Kristina Y. Aguilera, Huocong Huang, Wenting Du, Moriah M. Hagopian, Zhen Wang, Stefan Hinz, Tae Hyun Hwang, Huamin Wang, Jason B. Fleming, Diego H. Castrillon, Xiaomei Ren, Ke Ding, Rolf A. Brekken

Language: English

Topic: Pancreatic and Hepatic Oncology Research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362535237

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