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Supplementary Figure S8 from PAXIP1 Potentiates the Combination of WEE1 Inhibitor AZD1775 and Platinum Agents in Lung Cancer

Year: 2023

Type: supplementary-materials

Abstract: (A) TMA containing 68 patient-derived xenograft (PDX) tumor models stained with PAXIP1 and WEE1 (B-C) Two lung adenocarcinoma PDXs with PAXIP1 and WEE1 staining were used to perform ex vivo 3-D clonogenic assays with various concentrations of AZD1775 and cisplatin and tumor/control - T/C was measured by image analysis.

DOI: 10.1158/1535-7163.22507972.v1

Authors: Ankita Jhuraney, Nicholas T. Woods, Gabriela Wright, Lily Rix, Fumi Kinose, Jodi L. Kroeger, Elizabeth Remily-Wood, W. Douglas Cress, John M. Koomen, Stephen G. Brantley, Jhanelle E. Gray, Eric B. Haura, Uwe Rix, Alvaro N. Monteiro

Language: English

Topic: Cancer-related Molecular Pathways

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362535348

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