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Supplementary Figures S1-S2 and Supplementary Tables S1-S3 from Identification of the Serine Biosynthesis Pathway as a Critical Component of BRAF Inhibitor Resistance of Melanoma, Pancreatic, and Non–Small Cell Lung Cancer Cells

Year: 2023

Type: supplementary-materials

Abstract: Supplementary Table S1: Proteins upregulated follwoing vemurafenib treatment of SK-MEL-28VR1 cells. Supplementary Figure S1: PHGDH gene ablation of SK-MEL-28VR1 cells. Supplementary Figure S2: Gemcitabine induced sensitization of SK-MEL-28VR1 and BxPC3M1 cells to vemurafenib. Supplementary Table S2: Combination index values for gemcitabine+vemurafenib combination in SK-MEL-28VR1 cells. Supplementary Table S3: Combination index values for gemcitabine+vemurafenib combination in BxPC3M1 cells.

DOI: 10.1158/1535-7163.22508964.v1

Authors: Kayleigh C. Ross, Andrew J. Andrews, Christopher D. Marion, Timothy J. Yen, Vikram Bhattacharjee

Language: English

Topic: Melanoma and MAPK Pathways

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362535433

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