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Figure S7 from A Small-Molecule Inhibitor of WEE1, AZD1775, Synergizes with Olaparib by Impairing Homologous Recombination and Enhancing DNA Damage and Apoptosis in Acute Leukemia

Year: 2023

Type: other

Abstract: Combined AZD1775 and olaparib treatment is tolerated in vivo. A and B. Mice injected with a murine AML cell line were treated as described in the text. Complete blood counts (A) and weights (B) were obtained 10 days after leukemia transfer. Results are displayed as mean {plus minus} SEM from 2 independent experiments. *, P < 0.05. **, P < 0.01.

DOI: 10.1158/1535-7163.22508029.v1

Authors: Tamara B. Garcia, Jonathan C. Snedeker, Dmitry Baturin, Lori Gardner, Susan P. Fosmire, Chengjing Zhou, Craig T. Jordan, Sujatha Venkataraman, Rajeev Vibhakar, Christopher C. Porter

Language: English

Topic: PARP inhibition in cancer therapy

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362535799

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