Work

Figure S6 from Targeting IDH1 as a Prosenescent Therapy in High-grade Serous Ovarian Cancer

Year: 2023

Type: other

Abstract: Senescence induced by IDH1 knockdown is independent of ROS and DNA damage; addition of exogenous αKG rescues the repressive histone methylation; knockdown of IDH1 increases repressive histone methylation at E2F target genes. Related to Figure 5.

DOI: 10.1158/1541-7786.22512408.v1

Authors: Erika S. Dahl, Raquel Buj, Kelly E. Leon, Jordan M. Newell, Yuka Imamura, Benjamin G. Bitler, Nathaniel W. Snyder, Katherine M. Aird

Language: English

Topic: Ovarian cancer diagnosis and treatment

Subfield: Reproductive Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4362535992

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