Supplemental Figures 1-5 from LEF1 Targeting EMT in Prostate Cancer Invasion Is Regulated by miR-34a
Year: 2023
Type: supplementary-materials
Abstract: Supplemental Figures 1-5. Supplemental Figure 1. Expression levels of miR-34a, miR-1260, miR-206, miR-93, miR-324-3P andmiR-324-5P in four (LNCaP, LNCaP-LEF1, LNCaP-AI, LNCaP-AILEF1shRNA) PCa cell lines by real time qRT-PCR. U6 was used for normalization. Supplemental Figure 2. Conservation of the predicated miR-34a binding sites in the LEF1 3'UTR among species Supplemental Figure 3. Schematic diagram of luciferase constructs used for testing miR34a repression of LEF1 Supplemental Figure 4. Reciprocol negative regulation of miR34a by LEF1. There is an decrease in miR34a expression in cell line with high levels of LEF1. Supplemetal Figure 5. Schematic diagram delinateing the miR34a-LEF1-EMT axis in regulating PCa invasion.
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4362536256